Semaglutide has been found to be effective in promoting weight loss in clinical trials. In fact, it has been approved by the US Food and Drug Administration (FDA) for chronic weight management in people with a body mass index (BMI) of 27 kg/m2 or greater and at least one weight-related medical condition, such as high blood pressure, type 2 diabetes, or high cholesterol.
In a large clinical trial, people who took semaglutide lost an average of 15% of their body weight over 68 weeks, compared to just 2.4% in the placebo group. Semaglutide works by reducing appetite, increasing feelings of fullness, and slowing the rate at which food leaves the stomach.
It is important to note that semaglutide should be used as part of a comprehensive weight management plan, which may include a reduced-calorie diet and increased physical activity. Semaglutide is not a substitute for a healthy lifestyle, but it may be a helpful tool for some people in achieving and maintaining weight loss. However, as with any medication, it is important to talk to your doctor about the potential risks and benefits of semaglutide for weight loss, as well as any other treatment options that may be appropriate for your individual needs.